By J. Christopher States
This e-book illustrates the chemistry, toxicology, and well-being results of arsenic utilizing novel modeling strategies, case experiences, experimental info, and destiny perspectives.
• Covers publicity assets, healthiness hazards, and mechanisms of 1 of the main poisonous minerals within the world
• Helps readers comprehend strength future health results of arsenic, utilizing inhabitants stories, mammalian and invertebrate versions, and pharmacokinetic and toxicokinetic models
• Discusses results, epidemiology, real-life examples, and modes of motion for arsenic-induced illnesses, like lung melanoma, diabetes, cardiovascular and pulmonary ailments, and immunotoxicity
• Acts as a reference for toxicologists, environmental chemists, and possibility assessors and contains updated, novel modeling suggestions for scientists
• Includes destiny views on distinctive issues, like extrapolation from experimental versions to human exposures, biomarkers for phenotypic anchoring, and pathology of continual publicity
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Additional info for Arsenic : exposure sources, health risks, and mechanisms of toxicity
This solution became to be known as Fowler’s solution. It was used to treat many ailments including fever, asthma, syphilis, rheumatism, skin disorders, and leukemia [12, 45]. 2). Fowler’s solution was used up until the mid‐1900s when other medicinal agents were found to be more efficacious with lower toxicity. The medicinal use of arsenicals such as Fowler’s solution is not without adverse effect. Sir Jonathan Hutchinson, an English surgeon, reported at the Pathological Society of London in 1887 that the long‐term internal administration of arsenic at high doses could result in epithelial cancer .
80] WHO Fact Sheet Number 134 (2008).  J. Zhang, X. Zhang, Y. Ni, H. Li, Bioleaching of arsenic from medicinal realgar by pure and mixed cultures. Process Biochemistry 42 (2007) 1265–1271. 2 GEOGENIC AND ANTHROPOGENIC ARSENIC HAZARD IN GROUNDWATERS AND SOILS: DISTRIBUTION, NATURE, ORIGIN, AND HUMAN EXPOSURE ROUTES David A. 1 Scope and Structure In this chapter, the distribution, nature, and origins of arsenic hazards in groundwaters and soils are outlined, along with the biogeochemical processes that give rise to these distributions.
In addition to the numerous secondary Fe phases that can form and sequester arsenic under Fe‐reducing conditions, a number of studies have suggested that arsenic may be sequestered from solution under sulphate‐reducing conditions . However, while arsenic release has been shown to be rapid , sequestration of arsenic from solution is rate limited by thermodynamic and kinetic restrictions on the formation of mineral phases and the rate at which arsenic sorbs to their surface [113, 166]. To complicate matters further, the precipitation of arsenic bearing minerals such as As‐sulfide may be inhibited by the presence of reactive Fe(III) or Fe(II) in solution .